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How many hours between Klonopin doses

Children up to 10 years or 30 kilograms (kg) of body weight—Dose is based on body weight and must be determined by your doctor. The dose is usually 0.01 to 0.03 mg per kg of body weight per day, given in 2 or 3 divided doses. However, the dose is usually not more than 0.05 mg per kg of body weight. Your doctor may adjust your dose as needed If a single glass of wine and a small dose of klonopin, (clonazepam) it is prob ok to take it within several hours of the wine. Klonopin (clonazepam) will be in your body for up to 1.5 days, but much of the effect passes in hours. 5.7k views Answered >2 years ago. Thank. 2 thanks The initial daily dosage of Klonopin for panic disorder is 0.5mg to 1mg a day in divided dosages. Your doctor will increase or decrease your dose as needed. If you are taking Klonopin for social anxiety disorder, your doctor will probably start by prescribing you a low dose of the medication for a limited period of time (such as one week)

Clonazepam (Oral Route) Proper Use - Mayo Clini

  1. -Maximum dose: 20 mg/day Comments:-Dosage should be increased by no more than 0.25 mg to 0.5 mg every third day until the daily maintenance dose has been reached, unless seizures are controlled or side effects preclude further increase.-Whenever possible, the daily dose should be divided into three equal doses
  2. About 2.5 hours ago took .5 mg of klonopin. Then mabey half and hour later took 5mg of valium. Forgot I had taken the klonopin. I used to take 1.5 mg of klonopin a day. Am I in danger of an overdosage read mor
  3. o-clonazepam are detectable in the urine for about four days after the last use. Variables That Influence How Long Klonopin Stays in Your Syste

High doses of Klonopin can potentially lead to a dangerous overdose. As a depressant, Klonopin suppresses the nervous system, and in high doses, it can even suppress important functions. Depending on your size, age, and what the drug is prescribed for, a standard dose should be between 0.5 and 1 milligram. Doses between 2 and 3 milligrams can. Klonopin as needed is excellent as well as being well tolerated. All these reviews on Klonopin being addictive are only half true. There is a difference between addiction and being dependent. Certain individuals will abuse anything even coffee. They have many problems not only Klonopin. A well tolerated dose is between .5 mg and .75 mg once. Answered March 9, 2021 · Author has 93 answers and 59.4K answer views.5mg will kick in around 30mins - 1hr. Depending on empty stomach, metabolism from working out, if ever taken other meds that are similar before, etc. Effects can last anywhere from 5-12 hrs from my vantage point. Again, depends on many factors

0.5 mg PO at bedtime; increase dose by 0.5 mg q3-4days; not to exceed 6 mg/day. REM Sleep Behavior Disorder (Off-label) 0.25-2 mg PO 30 min prior to bedtime; not to exceed 4 mg. Burning Mouth Syndrome (Off-label) 0.25 mg PO at bedtime for 1 week; increase dose by up to 0.25 mg qweek; not to exceed 3 mg daily in 3 divided doses First dose - 9am Second dose - lunchtime (approx between 1pm and 2pm) Third dose - early evening 6pm Of course, check with your doctor for any special requirements you may have concerning your prescription, such as ensuring you take your medication either a) with food or b) on an empty stomach The medicinal effects of Klonopin however, last for shorter periods of time. The duration of action of Klonopin is between 6 to 12 hours. Therefore, if you wish to avoid additive sedation, you should wait at least that long before taking Percocet Don't know: You haven't said what the Klonopin (clonazepam) is for, or why you want to stop it. . But I think you said you are taking 0.5 mg daily -- that would meant only once a day. IF so, then you would not need to be concerned about withdrawal, since the dose is low.Instead, be concerned about whether your symptoms will return, and whether you have had adequate treatment When starting clonazepam, anxiety or insomnia may improve rapidly or over a period of days or within hours of the first dose of medication. Summary of FDA Black Box Warnings The FDA has found that benzodiazepine drugs, such as clonazepam, when used in combination with opioid medications or other sedating medications can result in serious.

Clonazepam doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight. Remove an orally disintegrating tablet from the package only when you are. Clonazepam, sold under the brand Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, and the movement disorder known as akathisia. It is a tranquilizer of the benzodiazepine class. It is taken by mouth. Effects begin within one hour and last between six and twelve hours. Common side effects include sleepiness, poor coordination, and agitation Klonopin's half-life is quite long, taking about 30 to 40 hours for the first half of the medication to leave your system. Depending on your Klonopin dose, this means it takes at least a week or two for your system to be cleared entirely of clonazepam. These lengths of time carry over into the amount of time it will take to pass a drug test Dose increases: A doctor may increase a child's dose by 0.25 to 0.5 mg every three days until their seizures are controlled. Maximum dose: 0.1-0.2 mg/kg per day taken in divided doses. Senior. Klonopin has a relatively long half-life, which refers to the length of time it takes for half of one dose of a drug to be eliminated from the body. For Klonopin, this time period ranges from 30-40 hours, meaning that it takes between 2-3 days for 50% of Klonopin to be expelled from a person's system

The initial daily dosage of Klonopin for panic disorder is 0.5mg to 1mg a day in divided dosages. 2 Your doctor will increase or decrease your dose as needed. How many mg of Klonopin is safe? Adults and children 10 years and older—At first, 0.5 milligram (mg) 3 times per day The benzodiazepine conversion calculator adjusts doses between converting oral benzodiazepines. This is an unprecedented time. It is the dedication of healthcare workers that will lead us through this crisis Klonopin is not a good prn medication. It takes at least two regular doses daily to build to a steady state. Then it actually prevents the anxiety attacks. Ativan and Xanax are usually given as needed For Klonopin, which has a half-life of about 30 hours, if you take 1 mg now, the time it takes for half the dose of the drug (0.5 mg) to be eliminated is 30 hours. In another 30 hours, the amount of drug that would have been eliminated is another half of the drug remaining in your body, or 0.25 mg Not only do more people use Klonopin, they use more than ever. Fox News continues, People with prescriptions received 1.4 times more medication in 2013 than 20 years earlier. The number of prescriptions has increased, as has the dose associated with each. Recreational or off-prescription use has likely risen as well

how much time should i wait in between doses of clonazepam

Klonopin for Social Anxiety: Dosage and Side Effect

Clonazepam Dosage Guide with Precautions - Drugs

Klonopin enters the bloodstream within 1-4 hours after ingestion, so while it does not act as quickly as other, more famous date rape drugs like Rohypnol, it is as likely in large enough doses to cause the individual to pass out. This is especially true when used in combination with alcohol, and it is harder to detect in alcoholic beverages One to four hours: 100 hours: Klonopin (clonazepam) One to four hours: 34 hours: Tranxene (clorazepate) 0.5 to two hours: 100 hours: Valium (diazepam) One to two hours: 100 hours: Dalmane (flurazepam) 0.5 to one hour: 100 hours: Ativan (lorazepam) One to four hours: 15 hours: Mogadon (nitrazepam) 0.5 to two hours: 30 hours: Serax (oxazepam) One.

2 X per day: 2 times per day every 12 hours 500mg. The daily maximum of 1500 mg in two divided doses. The daily maximum of 1500 mg in two divided doses. Always ask your doctor if you are unsure Klonopin is considered a rapid-acting benzodiazepine with an intermediate duration of action. After taking by mouth, it begins to work in 15-30 minutes and lasts between 6 and 12 hours per dose. Clonazepam metabolism does not create active metabolites and it is not thought to accumulate in the body. It does produce inactive metabolites (as. Both drugs may begin working within hours or days of the first dose. A dose of Xanax will affect you for a few hours. The effect of clonazepam lasts about two or three times as long The dosage range is 1 to 10 mg per day. A common recommendation is to take a new dose every four hours during the day. If anxiety symptoms return earlier than four hours, clonazepam is sometimes added to the alprazolam. Tapering. Generally physicians taper alprazolam at 0.25 mg every three days. Withdrawal and rebound symptoms can occur during. Levels of Klonopin peak in the blood between 1 and 2 hours after the last dose has been taken. It may be possible to detect a smaller amount of Klonopin prior to this time. A blood test may be the easiest way to detect the drug in the bloodstream. This method is commonly used in hospitals and other medical settings

How many hours apart should klonopin ,5 mg 3x aday be take

Alprazolam (Xanax), lorazepam (Ativan), estazolam , and temazepam are intermediate-acting agents with durations of action of 11 to 20 hours. Chlordiazepoxide , clonazepam (Klonopin), diazepam (Valium), flurazepam , and quazepam are long-acting agents with duration of action of 1 to 3 days Klonopin (clonazepam) and Restoril (temazepam) are benzodiazepine drugs used for the treatment of anxiety. Klonopin is also used to treat panic disorder, while temazepam is also used to treat insomnia symptoms, such as trouble falling asleep and staying asleep. Learn about the side effects, recommended dosage and main differences between these two anti-anxiety medications

How Long Does Klonopin Stay in Your System? The Recovery

By mouth. For Child 1-11 months. Initially 250 micrograms once daily for 4 nights, dose to be increased over 2-4 weeks, usual dose 0.5-1 mg daily, dose to be taken at night; may be given in 3 divided doses if necessary The duration of action of Klonopin is around 6 to 8 hours in children and up to 12 hours in adults. While the effects of Klonopin generally last 6 to 12 hours, the half-life of the drug (i.e. time it takes for 50% of the drug to be metabolized) is significantly longer, around 30 to 40 hours prescription drug time and dosage limits by creating an inventory of state legal strategies in this domain. Introduction To combat the prescription drug overdose epidemic, many states have enacted laws that set time or dosage limits on the prescribing or dispensing of controlled substances Clonazepam is available as 0.5 mg, 1 mg and 2 mg tablets. Dosing Information of Clonazepam for Dogs and Cats. Medication should never be administered without first consulting your veterinarian. The dose range for clonazepam has been reported as 0.05 to 0.25 mg per pound (0.1 to 0.5 mg/kg) orally every 8 hours

Klonopin enters the bloodstream and makes its way to the brain in an hour, while it can remain in the system for close to three days, depending on the size of the dose (the half-life is between 18 and 39 hours).. The Addiction Potential of Benzodiazepine Klonopin has a long half-life and remains in the system for a considerable amount of time: 30-40 hours. However, it takes about five half-lives before a substance is fully eliminated from the body, which means a single dose of Klonopin can stay in the system for up to a week KlonoPIN; KlonoPIN Wafers; Descriptions. Clonazepam is used alone or together with other medicines to treat certain seizure disorders (eg, Lennox-Gastaut syndrome, akinetic, myoclonic, and absence seizures). It is also used to treat panic disorder. Clonazepam is a benzodiazepine that works in the brain to prevent seizures She prescribed me 30 small doses of clonazepam, the generic for Klonopin, so I wouldn't have to call and refill it for a while. I never intended to take it unless my untreated anxiety launched me into extreme physical or emotional distress. Suddenly, that was all the time. Like Dunham's, my standard for extreme distress requiring.

Clonazepam oral tablet - Klonopin dosage 0.5 mg, 1 mg, 2 mg; Clonazepam oral disintegrating tablet - Klonopin dosages 0.125 mg, 0.25 mg, 0.5 mg, 1 mg, 2 mg; Xanax Dosage Forms. Xanax is available in immediate-release and extended-release oral tables. Immediate-release tablets may need to be taken many time per day Taking 1mg clonazepam and 10mg hydrocodone (Vicodin) nearly 4 hours later with somewhat of a klonopin tolerance led to uncomfortably shallow breathing laying down. Unable to get full breaths except once every so often and unable/ literally afraid to sleep because of fear of further respiratory depression Ativan/klonopin: Ativan can last 4-6 hours, Klonopin up to 12 hours.Also, Ativan can be injected and that is used in er for emergencies. There is a form of Klonopin (clonazepam) that works fast and can be dissolved on tongue, called Klonopin (clonazepam) wafers In the second study, it lasted for six weeks. This was a flexible Klonopin dose study that ranged from 0.5 mg to 4 mg per day or a placebo. There were three phases which included: A 1-week placebo introduction. A 6-week optimal-dose. A 6-week discontinuation dose. The average Klonopin dose within the optimal dosing period was 2.3 mg per day

Klonopin Use: How Much Is Too Much? - Serenity at Summi

I take Klonopin 1mg., Ambien 10mg., and Flexeril 10mg.,every night for sleep. I also take ZMA, a product sole here for sleep. I sleep wonderful.I get up and pea, and go right back to sleep. I have found that ambien can cause a form of amnesia, if I stay up too long after I take it Order Generic Xanax Pills online without a prescription. Best offers in 2018. Fast delivery to the U.S. and Canada Clonazepam For Sleep. Clonazepam, like trazodone, is used off-label for insomnia (i.e. it is not FDA-approved for this purpose). It belongs to a class of medications known as benzodiazepines and, in general, benzodiazepines have more side effects and have a higher potential for dependence, tolerance, and rebound insomnia

Xanax prescriptions for anxiety and panic disorders may range from 1 to 10 milligrams per day. Doses vary depending on the individual and form of Xanax (immediate or extended release) Clonazepam (Klonopin) is a common culprit. It belongs to a class of drugs called benzodiazepines. They have been use as sleeping agents for decades. It is a tranquilizer of the benzodiazepine class. similarly, consume it by mouth. And thus begins having an effect within 1 hour and lasts between 6 and 12 hours. clonazepam use Klonopin's long half-life means that metabolites of this drug will remain in the body for 5-14 days. If a person quits Klonopin suddenly, withdrawal symptoms will likely last up to two weeks, but that can vary depending on how long the person has struggled with Klonopin addiction and how large their regular doses were

1/2 life is 3 days: The dose that you write for Clonazepam is unclear . A typical starting dose is 0.5mg (4 times the dose you write). A typical starting dose is 0.5mg (4 times the dose you write). The higher the dose and the long. Can I take it before bed if I am taking generic Klonopin (1/2 pill not a hi dose and) and gen. Flexeril 10 mg I think for sleep at bedtime. Not sure how many hours it should be after taking the A.T to take the Calcium if in the morning. Taking Ca 3x a day is making it difficult to know or do what is right

dose. It is necessary to take the tablets several times a day and many people experience a mini-withdrawal, sometimes a craving, between each dose. For people withdrawing from these potent, short-acting drugs it has been advised that they switch to an equivalent dose of a benzodiazepine with a long half life such as diazepam (5). Diazepa Regular Xanax will work for about 5 hours, though it will remain in your body longer. Extended-release Xanax will work for about 11 hours. Ativan's effects last up to 8 hours. Both are broken down by the liver, so folks with liver disease will need to watch out for these drugs lasting longer than expected roprivot11120 3 Average dosage range for maintenance therapy: Age Daily Dose 0.5 mg Tablets Oral Liquid Drops Infants (up to 2 years) 0.5 - 1 mg 1 tablet - 2 tablets 5 drops - 10 drops Small children (2 - Personally, tramadol + klonopin was one of my favorite drug combos for years (which is saying alot, believe me). I only quite because of my horrible benzo/tram addiction.I am still of benzos, but back on the trams real bad again (which I promised myself I would never do, being that tramadol was the 2nd worst w/d I ever went through, next to a simultaneous high-dose, cold-turkey alprazolam. Based on the 30 to 40 hour half-life estimation of clonazepam, we can estimate that Klonopin is likely to stay in your system for 6.88 to 9.17 days after your final dose. Other sources suggest that clonazepam may have a wider ranging half-life between 18.7 hours to 60 hours

The length of time or how long this drug could stay in your system is measured in terms of half-life. The half-life of clonazepam is between 18 to 50 hours. This however depends on a number of factors that are mainly metabolic. This implies that the amount of the drug divides by half in your system after every 18 to 50 hours Oxazepam (Serax) has a slow onset, and lorazepam (Ativan), alprazolam (Xanax), and clonazepam (Klonopin) have intermediate onsets of action. Clorazepate (Tranxene), midazolam (Versed), and triazolam (Halcion) are short-acting agents with durations of action of 3 to 8 hours The combined half-life of diazepam and its active metabolites is over 200 hours and this produces an accumulation of 5-7 times the therapeutic action of diazepam. It takes up to eight weeks for most of the accumulated drugs to be eliminated from the body Clonazepam has an elimination half-life of 18 - 50 hours to 19 - 60 hours, and is generally considered to be a long-acting benzodiazepine. Clonazepam has an intermediate onset of action, with a peak blood level occurring one to four hours after oral administration

The drug's label clearly specifies that it is recommended only for short-term use—say, seven to 10 days—but once exposed to the pill's seductive side-effects, many patients come back for more. And not surprisingly, many doctors are happy to refill prescriptions to meet this consumer demand The dosage he prescribed was: to begin with 1/4 of a 500 microgram ( 0.05 mg) of clonazepam - to be upped to a whole one over time. As I say I have been taking it for four years now and have upped it in the last year to 1/2 at night - I wouldn't be without it now. Do make sure it is microgram dosage and not milligram as there is a huge. The below tables contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.The elimination half-life is how long it takes for half of the drug to be eliminated by the body 1 formulary drug 2 Rapid onset = within 15 minutes, Intermediate = 15-30 minutes, Slow = 30-60 minutes Rapid onset = within 15 minutes, Intermediate = 15-30 minutes, Slow = 30-60 minute Klonopin has a long half-life of between 30 hours and 40 hours, so it can take a few days for withdrawal symptoms to fully kick in. While individual experiences vary, Klonopin withdrawal often follows this general timeline after stopping use of the drug

Klonopin (Clonazepam) Dosage (0

This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. What if I miss giving my pet the medication? Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. Never give your pet two doses at once or give extra doses The first phase of Klonopin withdrawal is the early withdrawal phase. This phase begins when the last dose of Klonopin has finally left the user's bloodstream - about 30 to 40 hours after the last ingestion of the drug. When the clonazepam effect has stopped, the brain will experience a resurgence of symptoms the drug is designed to mitigate A Klonopin overdose is possible if a person takes more than the prescribed dose. Signs of a Klonopin overdose include: 1,2,3. Difficulty concentrating. Confusion. Slowed reflexes. Impaired coordination. Slurred speech. Drowsiness. Loss of consciousness. Coma. Call 911 immediately if you believe you or someone you know has overdosed on Klonopin Klonopin is detectable in blood plasma within half an hour of ingestion. It reaches peak levels in the blood between one and four hours after it's taken. Brain effects tend to occur within an hour of ingestion and can last for up to twelve hours. Drug tests can find the substance during this time and up to three or more days after use

How long does a 0.5 mg Klonopin pill take to start working ..

Study 2 was a 6-week, flexible-dose study involving Klonopin in a dose range of 0.5 to 4 mg/day or placebo. This study was conducted in three phases: a 1-week placebo lead-in, a 6-week optimal-dose, and a 6-week discontinuance phase. The mean clonazepam dose during the optimal dosing period was 2.3 mg/day. The difference between Klonopin Clonazepam, also called Klonopin, is a drug that is classified as a benzodiazepine, which acts as a tranquilizer in the body. Clonazepam is used to treat panic disorders, compulsive disorders, depression, and psychological disorders. Once an individual takes Clonazepam, the drug begins to work very quickly Clonazepam must be introduced gradually, and a low starting dose is advisable, such as 0.5 to 1.5 mg/day, which may be taken all at once or divided into two or three doses. The dosage can be increased by 0.5 to 1 mg every 3 to 7 days In addition, more than 75,000 people were admitted to the ER in 2011 due to complications caused by Klonopin. If high doses of Klonopin are used regularly over a long period of time, the user may develop a tolerance, which can quickly spiral out of control into habits of misuse and overuse Klonopin (Clonazepam) is a benzodiazepine drug that is commonly prescribed for management of epileptic seizures as well as anxiety and panic attacks. It is widely regarded as a first-line treatment option for seizures, but is not a viable long term treatment solution based on the fact that patients quickly develop a tolerance

Klonopin (clonazepam) dosing, indications, interactions

Klonopin is a potentially habit-forming benzodiazepine, with some people becoming addicted to it in as little as a few weeks.Many people have become addicted to Klonopin taking only the amount prescribed by their doctor. Klonopin blocks special receptors in the brain to reduce anxiety, stress, and difficulty relaxing klonopin d Clonazepam is marketed only as 0. 9k Members Klonopin dosage-anxiety jester76. There is a potency difference between clonazepam and Klonopin. [1] More people are taking more Klonopin. Long Duration (Variable) 1 mg: 15 mg (range 2 Clonazepam is not generally recommended for long-term use because it is known to be a habit-forming substance. Over time, the patient's body tends to build a tolerance to clonazepam. This means that the body adapts to the presence of clonazepam in its system, and the patient's usual dose of clonazepam ceases to be as effective

How Many Hours Apart Is 3 Times A Day? The Right Times To

The same applies with the combination of Methadone and Benzodiazepines The half life of the Clonazepam is 18 - 50 hours The half life of the Buprenorphine is 24 - 36 hours If you are tolerant to. Gabapentin comes in many sizes including 100, 300, 400, 600, and 800 mg. The usual dose is 1800-5400 mg a day but the dose can vary depending on how well it works for you and your tolerance of the medication. If you find a dosage level that is satisfactory, there is no reason to increase the medication The number of Klonopin overdose is continually increasing. In 1999, 1,219 people died from an overdose, compared to 2011 when 7,161 people died. High doses of the drug can slow vital functions and lead to stroke, cardiac arrest, respiratory complications, coma or death. Mixing Klonopin with alcohol or opioids increases the risk of a fatal overdose Clonazepam is known to work relatively fast, and it is often taken several times daily. The effects of Klonopin can last anywhere from 6 to 12 hours, but it can take between 30 to 40 hours to fully get rid of Klonopin in your body. Side Effects. The following are the most common side effects of Klonopin: Sleepiness or drowsiness. A case is presented of a fatal drug interaction caused by ingestion of oxycodone (Oxycontin) and clonazepam (Klonapin). Oxycodone is an opium alkaloid used in long-term pain management therapy. Clonazepam is a benzodiazepine used for the treatment of seizures and panic disorders. The Drug Abuse Warn

How Long To Wait After Taking Klonopin To Take Oxycodon

The Difference Between Xanax and Klonopin: Each dose is meant to last longer too. A patient will feel the results for a longer duration of time than with some other treatments. Now as for Xanax, this drug has a harder hit and it fades out quickly. Unlike its Klonopin counterpart, Xanax can be habit forming Hi Dear, Thank you very much for your information. As far as i know, half-life of elimination or Klonopin is between 18 hours to 50 hours or 19 hours to 60 hours (xanax is more or least 12 hours, not Klonopin!, so many books say that we can count more or least 30 to 40 hours. Am i right or do you have another source and everything in the Web is wrong

is long term low dose klonopin (clonazepam) use safe? i

Usually, Klonopin reaches the peak concentration in the blood 1 to 4 hours after you take it. Clonazepam and its breakdown products (metabolites) reach their peak concentrations 2 hours after a 2 mg dose is taken. Benzodiazepines including Klonopin, are fast-acting drugs. It means these drugs usually provide immediate effects You would do well to know your equivalents, i.e.: ten mg of Valium equals half an mg of Klonopin or Xanax and similarly, 20 mg of Valium equals one mg of Klonopin or Xanax. I have been told that if you dose Valium twice a day, 12 hours between the doses, it is certainly possible to maintain a level amount in your blood Klonopin is known as a long-lasting benzodiazepine. Its half-life is between 30-40 hours. This means that symptoms of withdrawal may take a while to become noticeable. Withdrawals from Klonopin can begin between 2-7 days following the last Klonopin dose

Clonazepam (Klonopin) NAMI: National Alliance on Mental

Get information on Clonazepam orally disintegrating tablets (wafers) including uses, dosage details, medication side-effects and drug interaction facts from Cleveland Clinic's health library. COVID-19 vaccine FAQs New visitation hours Need a COVID-19 test before travel, school or childcare? 800.223.2273 CLONAZEPAM (kloe NA ze pam) is a. I can't decide what the equivalence ratios for Ativan (lorazepam), Klonopin (clonazepam), and Valium (diazepam) are. I have heard that 0.5 mg Klonopin = 2 mg Valium, but I have also read on the internet that 0.5 mg Klonopin = 10 mg Valium. That is quite a large range Because of these problems, many individuals choose to use Klonopin for a relatively short time period. Once you have discontinued Klonopin, it can only stay in your system for a set amount of time. If you have been using Klonopin for an extended time period or at higher doses, your body may have developed a dependency to the drug

With a half life of up to 200 hours, Valium is often the wisest choice when switching from a shorter acting benzodiazepine - however, many find that the reasonably long half life of Klonopin to be adequate for tapering; it's only downside being the difficulty in getting the dosage precision right. (Please refer to The Ashton Manual for more detailed information about half lives and tapering. Therapeutic ranges are tentatively given as 20 to 30 ng/ml but dosage adjustments are best made on clincial grounds alone. The upper limit should be determined by the occurrence of any unacceptable side effects. Clonazepam should be given twice daily. Adult doses range between 1.5 and 20 mg a day; pediatric doses, from 0.01 to 0.2 mg/kg per day Klonopin takes anywhere from an hour to four hours to reach its peak effectiveness. The drug's half-life is 34 hours, which means that half of the medication is eliminated from the body within that time frame. By comparison, Valium takes between an hour and two hours to reach peak effect and the half-life is 100 hours These answers, along with the many that are regularly posted by Ben Young, M.D., Ph.D., on our Ask the Experts Forum on Choosing Your HIV Meds, paint an encouraging picture for people on HIV. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Do not take more than one dose of the extended-release tablets or capsules in 12 hours

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